Category: Biology

Open Access Referees

The new journal (Biology Direct), hopes to revolutionise the peer review process by placing the burden of selecting “referees” for a paer on the shoulders of the authors themselves and removing the protection of referee anonymity that has been the mainstay of the scientific publication system for decades, if not centuries.

The journal suggests that such an approach to peer review will increase “both the responsibility and the reward of the referees…eliminating sources of abuse in the refereeing process” and presumably reducing the risk of fraudulent results entering the scientific literature.

It remains to be seen whether referees will voluntarily expose themselves to the criticism of their peers for those papers they review, whether that’s authors wishing they’d picked someone else when a paper is slated, or rivals suggesting that a referee is at fault when a paper receives a positive review.

Worms Survived Shuttle Disaster

Nathaniel Szewczyk and colleagues are experts in the nematode worm Caenorhabditis elegans, this popular little organism has been the subject of countless biological studies including Nobel-prize winning efforts. As such, it is being developed as a model system for space biology.

According to Szewczyk, the chemically defined liquid medium, C. elegans Maintenance Medium (CeMM), allows it to be cultivated automatically and experiments to be carried out on it during spaceflight research. His team grew CeMM for experiments to be carried out on board STS-107, space shuttle Columbia.

When tragedy struck Columbia, a massive recovery effort was started and hardware containing the CeMM experiment was actually retrieved from the debris.

Szewczyk explains that live animals were observed in four of the five recovered canisters, which had survived on both types of media. “These data demonstrate that CeMM is capable of supporting C. elegans during spaceflight. They also demonstrate that animals can survive a relatively unprotected reentry into the Earth’s atmosphere, which has implications with regard to the packaging of living material during space flight, planetary protection, and the interplanetary transfer of life,” Szewczyk explains.

You can read more about this rather unusual rescue mission in the journal Astrobiology 5, 690—705
Astrobiology.

Fierce Biotech

Fierce Biotech

I’ve mentioned the Fierce Biotech freebie email biotech industry newsletter before, but it’s well worth reminding Sciencebase readers of what a great resource it is. It’s now available for free in the USA, Canada, Mexico, and the UK. All you have to do to qualify for a free year’s subscription is fill in your details on the form and provide a little feedback on your job function (so they can decide whether you qualify). Once you’ve done that, you’ll starting receiving the free email newsletter within a day or two. The Fierce Biotech ezine covers the latest industry news on a daily basis and your acceptance for a free subscription helps support Sciencebase.

Newsletter description – “FierceBiotech is an easy to read daily email service that brings must read biotechnology news to senior executives in the biotech industry…one quick email per day keeps you up to speed on biotech companies and the biotech industry.” This newsletter will save you time and effort in keeping ahead of the competition.

Fishy Smaller Fish

We reported on claims to have found the world’s smallest fish that appeared in the Proceedings of the Royal Society of London B. The aquatic critter measured just 7.9 mm apparently and was found in a peat swamp in Southeast Asia. However, it seems the authors of the paper failed to note that a much, much smaller sexually mature angler fish was reported in the autumn of 2005 at just 6.2 mm to 7.4 mm in length.

So, what’s a few millimetres between friends? The female of the species in question, Photocorynus spiniceps presumably sees the significance, she comes in at a wopping 46 mm (some 7 seven times longer than her mate).

The smaller fish was reported in the journal Ichthyological Research and according to the study, the male is essentially a sexual parasite. He fuses for life to the back of his mate by biting on and turns the female into a hermaphrodite, providing her body with everything she needs to reproduce, she provides the food and navigational skills.

Again, size is everything for this arduous task, male spiniceps have testes so unfeasibly large that they almost fill his entire body cavity, even to the point of crowding out his other internal organs. Still, what fish is going to care about his internal organs when he’s perpetually mating and getting fed in the process?

Accelerated Aging

Chemical analysis spots malfunctioning protein.

Jin-Shan Hu and colleagues at the University of Maryland, National Cancer Institute, the National Centre for Scientific Research, France, have used NMR to determine the structure of the protein thought to malfunction in premature aging conditions, such as Werner syndrome. The structure might one day lead to a better understanding of this rare genetic disorder as well as other aging-related diseases.

Medicating Male Orgasm

“Pour yourself a stiff one” Indeed! That’s the word on the pharma lecture circuit as drug companies work themselve up into a lather chasing liquid Viagra.. Meanwhile, there seems to be no end of new targets, even with malaria, cancer, TB, bird flu and the rest providing plenty of fodder, the pharma industry is intent on developing paying treatments for the likes of shyness, hypochondria, and of course premature ejaculation.

Dapoxetine was originally developed as a serotonin-reuptake inhibitor for depression. And, as male users of related quickly, or rather slowly, found out, these drugs cause retarded ejaculation. One man’s side-effect is another man’s therapy. Hence the repositioning, as it were, of Dapoxetine.

Anyway, the industry is, according to Alan Cassels writing in Canada’s CommonGround, keen to get into this new market, although the FDA deigned dapoxetine unapprovable saying that the manufacturer’s claims that it “�increased intra-vaginal ejaculatory latency (IEL) time” better than a placebo, did not stand up to closer examination. So, what will be the next big thing? Have you had enough of my puerile puns and blatant innuendos? Come again for more of the same!

Erotic pictures could cause brain crash

TL:DR – Visual overload caused by gore or phwoarrh can cause emotional blindness, according to research done in the USA back in 2005.

Forget Cronenburg’s Crash…

If you feel your viewing partner cannot see you while watching TV, it could be that the flash of nudity that was on the screen, just then, has caused emotional blindness. The same effect could lead to accidents if drivers succumb to this condition having seen a suggestive billboard.

Portions of the research exploring this effect by Vanderbilt University psychologist David Zald and Yale University colleagues was published in the August 2005 issue of Psychonomic Bulletin and Review.

“We observed that people fail to detect visual images that appeared one-fifth of a second after emotional images, whereas they can detect those images with little problem after neutral images,” Zald said.

Anyone who has ever slowed down to look at an accident as they are driving by–or has been stuck behind someone who has–is familiar with the “rubbernecking” effect. Even though we know we need to keep our eyes on the road, our emotions of concern, fear and curiosity cause us to stare out of the window at the accident and slow to a crawl as we drive by. The same thing seems to happen whether it gore or phwoarr!

Study: Genistein in soya may harm male fertility

I found an interesting write-up of that soy and sperm story I blogged yesterday: Genistein in soya

The author makes a similar point to me: “The study does not reveal how genistein would affect in vivo human sperm.”

But, then he says, “In reality, Asian people use a lot of soya products, but they don’t seem to have a fertility problem.” What does he mean “in reality”? As opposed to “in the laboratory?”, “in virtuality?”, “on TV?”, what? Anyway, how does he know that Asian people don’t suffer fertility problems, is he assuming that because the populations of Asian countries are high that individuals are fecund?

Anyway, back to the science – the isoflavone genistein has been shown in separate studies to have estrogenic and anti-estrogenic properties and also to be a cancer protective. But, then others have shown it to cause uterine cancer…I don’t suppose we’ll ever know the truth, especially given that much of the research into the health benefits of soya products has been funded over the years by soya manufacturers.

Soybean Sperm Assassin

According to the BBC today, soybeans, peas, and French beans can affect fertility. Apparently, women shouldn’t eat these leguminous veggies because they can damage sperm. Surely it should be men that ought to avoid these vegetables…or is it that eating them releases something into the female reproductive tract that seeks and destroys sperm? The BBC didn’t say.

One thing that should be pointed out is that the researchers in question have only demonstrated the effect in the laboratory, said The Beeb. I reckon those researchers ought to be more careful about what they get up to in their lab, testing out their fertility on each other…

One other thing, before I go, according to http://www.nulldrweil.com/u/QA/QA89074/ if you’re undergoing IVF then both partners need to up their zinc intake and guess what he cites as the best vegetarian sources of Zn…legumes (dried beans, garbanzos, black-eyed peas, lentils, peas, soy products and whole grains).

Talk about conflicting evidence.