A recent live Webcast gave Professor K. Barry Sharpless, the 2001 Nobel Prize Winner in Chemistry, the opportunity to explore the intricacies of scientific discovery and how it is that when observation is concerned, good luck favours only the prepared mind.
Video no longer available, sorry.
Neither the video nor the sound quality were great anyway. The organisers also ran a one-on-one interview with Sharpless. You might have also watched student reactions to the Sharpless lecture.