Back in the day, when I was freelancing regularly for New Scientist, the magazine covered the story of the errant webs created by spiders that had been exposed to (THC) from marijuana, LSD, speed and various other drugs including caffeine and alcohol . This was an issue in 1995, if I remember rightly. There was a follow up a “humourous” video many years later, which you can watch here:
As you can see the spiders don’t do their best work when they’re stoned on various psychoactive drugs and the social outcomes are not optimal it has to be said. The original New Scientist story from 1995 is here (paywall); perhaps surprisingly the research was done by NASA.